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SEMAGLUTIDE

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CAS No. 910463-68-2

Semaglutide

Basic Information

ItemInformation
Product NameSemaglutide
SynonymsGLP-1 Analog
CAS No.910463-68-2
Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight4113.58
AppearanceWhite to off-white lyophilized powder
Purity≥ 98%
StructureGLP-1 receptor agonist peptide

Product Description

Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist designed for the treatment of metabolic disorders.

It enhances insulin secretion, reduces glucagon release, slows gastric emptying, and promotes satiety. Because of these mechanisms, semaglutide is widely used in pharmaceutical research and drug development targeting diabetes and obesity.


Applications

Typical applications include:

  • Pharmaceutical API development

  • Diabetes drug research

  • Anti-obesity drug development

  • Peptide synthesis research

  • Metabolic disease studies


Specification (Typical)

PROPERTIES

LIMITS

RESULTS

APPEARANCE

WHITE OR ALMOST WHITE POWDER

CONFORMS

SOLUBILITY

SOLUBLE IN WATER

CONFORM

WATER CONTENT (KARL FISCHER)

≤8.0%

6.9%

SODIUM SALT

≤5.0%

1.9%

ACETIC ACID (BY HPLC)

≤0.1%

ND

TFA

≤0.5%

ND

AMINO ACID COMPOSITION

HIS: 0.9-1.1

0.9

ASP:0.9-1.1

1.1

ALA: 2.7-3.3

3.1

VAL :1.8-2.2

2.0

GLU :4.5-5.5

5.0

LEU :1.8-2.2

1.8

GLY:3.6-4.4

3.9

LYS: 0.9-1.1

1.0

THR: 1.8-2.2

2.0

LLE: 0.9-1.1

1.1

PHE: 1.8-2.2

2.1

ARG:1.8-2.2

1.9

SER:2.7-3.3

3.0

TYR: 0.9-1.1

0.9

AIB:N/A

DET

AEEA:N/A

DET

PEPTIDE PURITY(BY HPLC)

≥98.0%

99.5%

RELATED SUBSTANCE

TOTAL IMPURITIES (%)≤2.0%

0.2%

LARGEST SINGLE IMPURITY( %)≤1.0%

0.5%

PEPTIDE CONTENT

≥85.0%

91.1%

ORGANIC SOLVENT RESIDUE

ACETONITRILE≤0.041%

<0.041%

DICHLOROMETHANA≤0.060%

<0.060%

N,N-DIMETHYLFORMAMIDE≤0.088%

<0.088%

BACTERIAL ENDOTOXIN

≤10EU/MG

<10EU/MG

MICROBIAL LIMIT

TOTAL AEROBIC BACTERIA≤100CFU/G

CONFORM

MOULD & YEAST≤10CFU/G

CONFORM

COLIFORM: ABSENT

CONFORM

PSEUDOMONAS: ABSENT

CONFORM

STAPHYLOCOCCUS: ABSENT

CONFORM


(Actual specifications depend on batch COA.)


Packaging

Standard packaging options:

  • 10 mg / vial

  • 100 mg / vial

  • Custom packaging available


Storage

Store at -20 °C for long-term storage.
Protect from moisture and light.

Shelf life: 2 years under recommended storage conditions


Supply Information

  • MOQ: 10 mg

  • Origin: China

  • Lead Time: 1–2 weeks

  • Shipping: Cold chain shipping recommended


Documents Available

  • COA (Certificate of Analysis)

  • MSDS (Material Safety Data Sheet)

  • Technical Data Sheet


Contact

For quotation, technical information, or documentation, please contact:

Ronas Chemicals Co., Ltd.

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