ACETYL HEXAPEPTIDE-8/ ARGIRELINE ACETATE

SECTION 1 – IDENTIFICATION

MSDS Name: ARGIRELINE ACETATE/ACETYL HEXAPEPTIDE-3/8  

Material Uses: Active ingredient in cosmetic and personal care applications.

Molecular Formula     : 868844-74-0

Company Identification: RONAS CHEMICALS IND. CO., LTD.

For information call：+886-2-8509-8500

For emergencies call：+86 198-8106-6898

SECTION 2 – HAZARD(S) IDENTIFICATION

Hazard classification (GHS classification): No harm.

Hazard risk description: No harm.

Precautions: Avoid contact with eyes, such as contact with eyes: rinse repeatedly with water, if wearing

contact lenses, remove the contact lenses first and then rinse. Other hazards: None..

SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS

INCI Name :  Argireline Acetate/Acetyl Hexapeptide-3/8

CAS No :616204-22-9

Purity: ≥97%

SECTION 4 - FIRST-AID MEASURES

Eyes: Rinse with water immediately.

Note: Symptomatic treatment.

Skin: Wash thoroughly with water and soap or anhydrous detergent after cleaning.

Oral: medical observation.

Important symptoms and harmful effects: Normal use has no significant adverse effects. Take appropriatefirst aid measures according to the patient's specific condition.

SECTION 5 - FIRE-FIGHTING MEASURES

Hazard characteristics: Be careful, it may decompose to produce toxic smoke when burning or at high temperature.

Fire extinguishing method: Firefighters must wear gas masks and full-body fire suits to extinguish the fire in the upwind direction. Move the container from the fire to the open space as much as possible. Spray water to keep the fire container cool until the fire is over. If the container in the fire has changed color or produced sound from the safety pressure relief device, it must be evacuated immediately. Spray the escaping liquid with water to dilute it into an incombustible mixture, and use atomized water to protect

firefighters.

Extinguishing agent: Atomized water, foam, dry powder, carbon dioxide.

SECTION 6 - ACCIDENTAL RELEASE MEASURES

Precautions for personal protection: Avoid eye contact, keep the container closed, and do not take it orally.

Elimination method: Remove possible combustible materials, wipe them off or shovel them into

containers for recycling or discarding. Use a vacuum cleaner, and use water washing or wet wiping.

SECTION 7 - HANDLING AND STORAGE

Precautions for operation: Avoid leakage and contact with eyes during operation.

Precautions for storage: It should be stored at 2-8℃ in a dry and cool environment. Stay away from sparks

and flames. This product is non-dangerous, so acid and alkaline impurities should be prevented from

mixing during storage and transportation.

SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION

Contact limit: Not specified.

Ventilation equipment: Ordinary level ventilation, no need for local intensive ventilation.

Respiratory system protection: Not specified.

Use proper breathing apparatus: Not specified.

Eye protection: Wear protective glasses for chemical work.

Hand protection: Not specified.

Skin protection: Wash your hands before eating and after handling.

Personal hygiene measures: Not specified.

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical form: White or almost white powder

Smell: Specific odor of product

Water solubility: Good

SECTION 10 - STABILITY AND REACTIVITY

Chemical stability: Unstable in case of high heat, it should be stored at 2-8℃ in a dry and cool environment.

Reaction risk: No dangerous polymerization reaction occurs.

Conditions to be avoided: None

Prohibited compounds: Oxidizing materials may react with this product, so contact with them should be avoided.

Decomposition products: None

SECTION 11 - TOXICOLOGICAL INFORMATION

Effects and symptoms of overexposure: There is no relevant report.

Eye: There is no relevant report.

Skin: There is no relevant report.

Inhalation: There is no relevant report.

Eating by mistake: There is no relevant report.

Other hazard information: There is no relevant report.

SECTION 12 - ECOLOGICAL INFORMATION

Eco-toxic effects: No data available.

Acute effects: No data available.

Degradability: Degradation of peptide chain in soil.

Bioaccumulation : No data available

Other harmful effects: No data.

SECTION 13 - DISPOSAL CONSIDERATIONS

Disposal method of product waste: It is not regarded as hazardous waste. Please contact the local environmental protection department and material recovery department for specific matters.

Disposal method of packaging waste: Recycle it in the normal way. Please contact the local environmental protection department and material recycling department for specific matters.

SECTION 14 - TRANSPORT INFORMATION

Road and rail transportation: Conventional transportation, without any restrictions.

Maritime transportation (IMDG): Conventional transportation, without any restrictions.

Air transport (IATA): Conventional transport, without any restrictions.

Special requirements and other information: None.

SECTION 15 - REGULATORY INFORMATION

Applicable regulations: People's Republic of China (PRC)-Hygienic Standard for Cosmetics

SECTION 16 - OTHER INFORMATION

This product shall not be used for food, medicine, medical treatment and related purposes, and our company does not make any express or implied guarantee for this.

We guarantee that the data in this material is based on our existing data, and we will reserve the right to modify this data. The data provided in this document cannot be used as technical standards. This information can only be used as a basic reference for general industrial hygiene and safety production procedures, but every user should clearly realize that in a specific use situation, careful and detailed audit should be carried out before use to determine the correct use method, and only careful evaluation is correct.

PROPERTIES

LIMITS

RESULTS

APPEARANCE

WHITE OR OFF-WHITE POWDER

CONFORMS

IDENTITY BY HPLC

THE RETENTION IS SAME WITH THE

REFERENCE SUBSTANCE

CONFORMS

IDENTITY BY MS

888.99±1

888.54

SOLUBILITY

≥100MG/ML(H₂O)

CONFORMS

PEPTIDE PURITY (BY HPLC)

≥98.0%

99.17%

RELATED SUBSTANCES BY (HPLC)

TOTAL IMPURITIES(%)£2.0%

0.83%

WATER CONTENT (KARL FISCHER)

£5.0%

3.38%

ACETIC ACID CONTENT

£5.0%

1.98%

TFA CONTENT

£1.0%

N.D

PEPTIDE CONTENT

≥85.0%

93.85%

HEAVY METALS

£10PPM

CONFORMS

TOTAL AEROBES COUNT

£100CFU/G

<10CFU/G

MOLD&YEAST

£10CFU/G

<10CFU/G

PATHOGENIC BACTERIA

N.D

CONFORMS

RESIDUAL SOLVENT

ACETONITRILE£410PPM METHYLENE CHLORIDE£600PPM

N,N-DIMETHYLFORMAMIDE£880PPM

ISOPROPYL ETHER£500PPM METHANOL£3000PPM

N.D

N.D

N.D

N.D

N.D