finasteride|RONAS CHEMICALS IND.CO.,LTD.

MSDS of Finasteride

Material Safety Data Sheets of Finasteride

1. Identification of Substance and of Manufacturer
Product Name: Finasteride
Manufactune's Name: Ronas Chemicals Ind. Co., Ltd.
For emergency or information's on health hazards call:0086 28-86082869

2. Data on substance
Product Name : Finasteride Code number:
Chemical name: 1,(5a)-androstan-4-aza-3one-17beta@N-tert-butylcarboxamide)
CAS number: 98319-26-7 EINECS number: Chemical family: Steroids
Therapeutic category:
Fromula: C23H36N2O2 Molecular weight:372.54

3. Hazard Identification
Hazard designation: Xn (Harmful)
Threshold limit value(TLV): Not established
Routes of absorption: Dermal(¡Á) Inhalation(¡Á) Ingestion(¡Á)
Effcet of over exposure:
4. Emergenc/and First Aid Procedure
Remove from exposure. Remove contaminated clothing. Persons developing serious
Hypersensitivity reactions must receive Immediate medical attention. Remove the fresh air.
Inhalatior: May cause irritation of respiratory tract. Avoid Inhalation. Remove to fresh air.
Eyes: May cause irritation. Flush with copious quantities of water.
Skin: May cause irritation. Flush with copious quantities of water.
Ingestion: May cause irritation. Flush out mouth with water.

5. Fire and Explosion Hazard Data
Extinguishing media: Water spray, dry chemicals, carbon dioxide or foam as appropriate for surrounding fire and materials.

Special fire fighting procedures: Evacuate personnel to safe area. Fire-fighters should use self-contained equipment and protective clothing.

Unusual fire and explosion hazards: Combustible. Ground mechaincal equipment to dissipate potential static electricity build-ur. Emits acrid and toxic fumes under fire condition.
6 Spill or Leak Procedures
Steps to be taken if material is released or spilled: Water suitable to protective clothing, approved respirator and rubber gloves. Vacuum or sweep up spillage.
Avoid dus : Place spillage in appropriate container for waste disposal. Wash contaminated clothing before reuse. Ventilate area and wash spill site.
Waste disposal method: Disposse off waste in accordance with applicable national and local laws regarding disposal of medicinal waste.

7. Handing and storage.
Precaution to be taken in handing and storing: Store at room Temperature in tight container with protection from light and humidity.
Other pregautions: Avoid contact with eyes, skin or clothing. Avoid breathing dust or mist. Use with adequate dust control. Wash thoroughly after handing.

8. Special Protection Information's
Respiratory protection: NIOSH approved respirator.
Ventilation: Adequate Local exhaust: Recommended
Mechaincal: Recommended
Protective gloves: Rubber or PVC eye protection: Safety goggles
Other protective equipment: Appropriate laboratory apparel, protect exposed skin.
9 Physical and Chemical Data
Appearance and odour: White or almost white crystalline powder, odorless
Biolling point: N.A. Melting point:251253degree C
Vapour density: N.A. Vapour pressure: N.A.
Evaporatior rate: N.A. Flash Point: N.A.
Flammable limits: N.A. Auto-ignition Temperature: N.A.
Reactivity in water: N.A. PH: N.A.
Solubility: Partially insoluble in water; very soluble in dichloro methane; freely soluble in acetone; soluble in methanol; sparingly soluble in ethanol.
Note: N.A.: Not applicable

10 Reactivity and Stability Data
Stability stable Incompatibility(material to avoid): Strong oxidant
Condition to avoid: Material is stable from a safety point of view.
Hazardous decomposition products: When heated to decomposition it emits acrid smoke and fumes.
Hazardous polymerisation: Will not occur.

11 Toxicological Information's
Toxicity data:
12.Ecologlcal Information's
No data is available regarding risks to waterways. Avoid that the product Id discharged Into waterways or drains which can contaminate groundwater.
Product Name: Finasteride Code number:

13. Considerations Regarding Disposal
Do not dispose of product together with domestic waste; Do not discharge into sewer. Dispose of by incineration.
Contaminated packing material: Dispose of in accordance with local regulations.
14. Information Regarding Transport
ADR/RID Transport by roadl/rall: No restrictions
LCAO/IATA Air transport: No restrictions

15. Regulatory Information
Classification according to EC Dircetive:
Symbol: Xn(Harmful)
Risks?
R20/21/22 Harmful by Inhalation , in contact with skin and if swallowed.
R36/37/38 Irritating to eyes, respiratory system and skin.
Safety recommendations (S)
S22 Do not breathe dust
S24/25 Avoid contact with skin and eyes.

16. Other information
This material safety Date Sheet was prepared in accordance with EEC Directive 93/112 of Dec.10,1999 and is intended to assist the recipient in complying with own obligations. The data contained in this documents was that available at the time of its preparation and was compiled from the following sources: Merck Index, Martindale-The Extra Pharmacopoeia, Sax. This information is intended for safety purposes only when the product id uses for pharmaceutical purposes and is not a guarantee of the product characteristics.