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BENZOCAINE
SYNONYMS:	Anesthesin;Parathesin;AuralganOtic; Ethylaminobenzoate;Ethyl4-aminobenzoate
CAS NO.:	94-09-7
EINECS NO.:	202-303-5
FORMULA:	C9H11NO2
H.S. CODE:	3004.90
CLASS NO.:	N/A
UN NO.:	N/A
NFPA:	2-1-0
DESCRIPTION:	A white,Crystalline Powder or colorless crystals Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA); it can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water, though is more soluble in dilute acids and very soluble in ethanol, chloroform and ethyl ether. The melting point of benzocaine is 92-94 degrees Celsius, and the boiling point is 310 degrees Celsius. The density of benzocaine is 1.17 g/cm3.
APPLICATION
Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter anesthetic ointments (e.g. products for oral ulcers of Anbesol by Wyeth, Kank+a by Blistex, Orabase B and Orajel by Del Pharmaceuticals, and Ultracare by Ultradent). It is also combined with antipyrine to form A/B Otic Drops, (Brand name Auralgan) to relieve earpain and remove cerumen.
SPECIFICATION & PACKING
Content: 99-101% Appearance: A white,Crystalline Powder or colorless crystals Formula: C9H11N09 Moisture: ≤0.1%  Loss on Drying: ≤0.5%  Residue on ignition: ≤0.1%  Melting Point: 89-92ºC  Heavy Metals: ≤10PPM  Acidity or Alkalinity: Conform Chloride: Conform Readily Carbonizable Substances: Conform Ordinary Impurities: Conform Packing: 25KG net fiber drum lined with plastic bag Storage: in well closed original container, between 5°C and 25°C
RAW MATERIAL:		N/A
END GOODS:		N/A
REMARKS:		N/A
MATERIAL SAFE DATA SHEETS

1. Identification of the product Benzocaine

Medical Device Class (according to 93/42/EEC) : FDA Nr :

Main use of the product: adhesive and analgesic dental plate paste

2. Composition

Substances CAS Nr R-phrases

Benzocaine 94 - 09 - 7

Oxychinolin Sulfate 134 - 31 - 6

Eugenol 97 - 53 - 0

Ethyl Alcohol 64 - 17 - 5

Sodium Carboxymethylcellulose 9004 - 32 - 4

Vaseline 8009 - 03 - 8

Water 7732 - 18 – 5

3. Hazards identification

To man: risk of allergy to Benzocaine

To environment: none for the considered quantities

4. First aid measures

Inhalation: -

Skin contact: rinse with water

Oral tissue contact: -

Eye contact: abundantly rinse with water, consult with an ophthalmologist

Ingestion: consult with a physician

Other recommendations: if allergy, stop treatment and rinse with warm water

5. Fire fighting measures : not applicable

Suitable extinguishing media: -

Extinguishing media not to be used: -

Special exposure hazards: -

Special protective equipment: -

6. Accidental release measures

Personal precaution: -

Environmental precaution: -

Method for cleaning up: soapy water

7. Handling and storage

Handling: -

Storage: in well closed original container, between 5°C and 25°C

8. Exposure control / Personal protection

Precautionary measures to be taken during use: see leaflet enclosed to the original packing

Respiratory protection: -

Hand protection: -

Eye protection: -

Skin protection: -

Soft oral tissues protection: -

9. Physical and chemical properties

Appearance: greasy paste Solubility: -

Odour: sharp and aromatic Insolubility: water, Ethyl Alcohol

Colour: yellowish Density: 0.96

pH: 6 Melting point: 60°C

Flammability: - Boiling point:

Other data: -

10. Stability and reactivity

Stability: 5 years

Conditions to avoid: heat, humidity

Materials to avoid: -

Hazardous decomposition products: not reported

11. Toxicological information

not reported, may be the cause of allergies

12. Ecological information

see point 3.2

13. Appropriate method of disposal

dustbin (empty tube) pharmacy (other)

Respect any national or regional provisions which may be in force.

14. Transport information

UN regulation: ID 8000

Custom’s harmonized tariff Nr: 3004.90

15. Regulatory information

for dental use only

16. Other information

Recommended use: for dental professional use only

Restriction of use: other than dental

CERTIFICATE OF ANALYSIS